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Conolidine’s analgesic results stem from its interaction with non-opioid pain pathways. Contrary to opioids, which bind to µ-opioid receptors while in the central nervous process, conolidine modulates alternate molecular targe… Read More

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Elucidating the precise pharmacological mechanism of motion (MOA) of naturally occurring compounds may be complicated. Though Tarselli et al. (60) created the main de novo synthetic pathway to conolidine and showcased that thi… Read More